Table 1.

Detailed quantification of the corpus callosum and anterior commissure in Slc12a6 cKO lines (n = 35)

Line	Slc12a6Δ18/Δ18	nsSlc12a6Δ18/Δ18
CPLa (mm)
WT	8.8 ± 0.32	8.85 ± 0.27
cKO	8.9 ± 0.33	8.85 ± 0.26
p value	0.207, ns	1, ns
CCL (mm)
cKO	3.5 ± 0.05	3.78 ± 0.03
WT	3.84 ± 0.047	3.88 ± 0.03
WT–cKO	0.34 (9.3%)	0.10 (2.6%)
p value	<0.001	<0.05
CCL/CPL ratio
WT	0.44 ± 0.023	0.45 ± 0.023
cKO	0.39 ± 0.024	0.43 ± 0.017
p value	<0.001	<0.001
AC (mm2)b
cKO	0.119 ± 0.003	0.14 ± 0.004
WT	0.144 ± 0.0048	0.146 ± 0.004
WT–cKO	0.024 (18.2%)	0.006 (4.2%)
p value	<0.001	0.16, ns
AC and the CC angle
WT	45.5° ± 0.32°	47.6° ± 0.38°
cKO	49.1° ± 0.37°	47.8° ± 0.35°
cKO–WT	3.6°	0.2°
p value	<0.001	0.77

The percentage differences between cKOs and WTs were calculated using 200 × (X_cKO − K_WT)/(X_cKO + X_WT) formula.

^aANOVA with Bonferroni correction.

^bLinear regression was used to adjust commissure sizes to average brain weight (see Materials and Methods). Mean ± SE, ns: not significant.