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. 2011 Oct 26;31(43):15294–15299. doi: 10.1523/JNEUROSCI.0921-11.2011

Figure 2.

Figure 2.

miRNA expression analysis using microarrays. Pearson's correlation scatter plot of miRNA levels in sham-operated and nerve-ligated mice at 7 d after surgery in the limbic forebrain (LFB) including the N.Acc. (r = 0.9865) (A-i), amygdala (Amy) (r = 0.8625) (B), and hippocampus (HC) (r = 0.9868) (C). A-ii, Heat map of 17 miRNAs that are differentially expressed in the LFB including the N.Acc. of nerve-ligated mice compared with that in sham-operated mice. Each miRNA is represented as a single bar based on its Ct value and the color coding represents a gradient from green (negative and lowest Ct values) to red (positive and highest Ct values). D–G, Quantitative analysis of miR34c, miR200b and miR429 expression in the LFB including the N.Acc. D, frontal cortex (FC) (E), hippocampus (HC) (F), and amygdala (Amy) (G) of mice at 7 d after nerve ligation. Each column represents the mean ± SEM of 3 samples. **p < 0.01, ***p < 0.001, sham-operated mice vs nerve-ligated mice.