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. Author manuscript; available in PMC: 2019 Oct 11.
Published in final edited form as: J Med Chem. 2018 Sep 26;61(19):8658–8669. doi: 10.1021/acs.jmedchem.8b00655

Figure 2.

Figure 2.

Plasma stability of phosphonamidate prodrugs. A) POM2-C-HMBP was exposed to 50% pooled human plasma in PBS for indicated time points. The graph indicates the mean fraction remaining and error bars represent standard deviations. Each data point was evaluated 2–4 independent times. B) The stability of the indicated phosphonamidates at 2 or 24 hour time points. Each data point was evaluated 2 independent times.