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. Author manuscript; available in PMC: 2020 Aug 15.
Published in final edited form as: Birth Defects Res. 2019 Apr 15;111(14):967–981. doi: 10.1002/bdr2.1505

Table 2.

Estimated mean and standard deviation for daily intake of total kilocalories, macronutrients, vitamins, and elements, from dietary sources only for mothers of cases and mothers of controls using the Food Frequency Questionnaire.

Nutrients Cases (n=55) Controls (n=55) DRI p-value
Total Energy (Kcal) §§c 2545 ± 1180 2218 ± 530 ND 0.071††
Macronutrients
Carbohydrates (g) §§a 377 ± 267 292 ± 77 175 0.002††
Protein (g) 148 ± 57 159 ± 55 71 0.272
Fat (g) 41 ± 18 40 ± 16 ND 0.691
Dietary Fiber (g) §§a 34 ± 15 26 ± 8 28 <0.001††
Percent Carbohydrate (%) 59 53
Percent Protein (%) 23 29
Percent Fat (%) 15 16
Vitamins
Vitamin A (µg) §§b 471 ± 211 406 ± 151 770 0.049
Vitamin A1 (µg) §§c 343 ± 183 293 ± 122 ND 0.065
Thiamin (Vitamin B1) (mg) §§a 1.5 ± 0.4 1.3 ± 0.3 1.4 0.008
Riboflavin (Vitamin B2) (mg) 1.8 ± 0.6 1.8 ± 0.6 1.4 0.615
Niacin (Vitamin B3) (mg) §§c 25 ± 12 21 ± 9 18 0.087††
Vitamin B6 (mg) 2.1 ± 0.7 1.9 ± 0.6 1.9 0.131
Dietary Folate (Vitamin B9) (µg) §§a 297 ± 125 242 ± 81 600 0.005††
Vitamin D (µg) §§b 4.8 ± 2.5 3.9 ± 2.0 15 0.023
Vitamin C (mg) §§a 205 ± 217 144 ± 110 85 0.013††
Vitamin E (mg) §§b 4.8 ± 2.0 4.1 ± 1.9 15 0.018††
Elements
Calcium (mg) §§a 1017 ± 558 1377 ± 680 1000 0.001
Copper (mg) §§a 3.3 ± 1.1 2.9 ± 0.7 1 0.010††
Iron (mg) §§b 18 ± 6 20 ± 8 27 0.048
Magnesium (mg) §§c 488 ± 185 433 ± 123 350 0.100††
Phosphorus (mg) 1757 ± 557 1716 ± 505 700 0.687
Potassium (mg) 3135 ± 941 2946 ± 1128 4700 0.317††
Sodium (mg) 570 ± 186 530 ± 165 1500 0.247
Zinc (mg) §§b 17 ± 7 14 ± 5 11 0.036††

Dietary Reference Intakes for pregnant women aged 19–30 (Office of Dietary Supplements, no date). Values marked with † are Adequate Intakes (AI). All other values are the Recommended Dietary Allowance (RDA) and data not available is indicated as No Data (ND).

Reported as Retinol Activity Equivalent.

§

Percent total energy intake for carbohydrates, proteins, and fat estimated by 4 kcal/g for carbohydrates and proteins and 9 kcal/g for fat.

Reported p-value for comparison between cases and controls using a paired t-test unless indicated differently.

††

Reported p-value from a Wilcoxon Signed Rank test.

§§a

Meets criteria for False Discovery Rate test at q=0.05, q=0.10, and q=0.15.

§§b

Meets criteria for False Discovery Rate test at q=0.10 and q=0.15.

§§c

Meets criteria for False Discovery Rate test at q=0.15 and above.