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. Author manuscript; available in PMC: 2019 Aug 21.
Published in final edited form as: Rheumatology (Oxford). 2017 Dec 1;56(12):2145–2153. doi: 10.1093/rheumatology/kex340

Table 3. Baseline characteristics of ACPA-positive/Rheumatoid Factor-positive patients that progressed to RA and did not progress to RA during 2 year follow-up.

Patient characteristic Convertors
(N=12)
Non-convertors
(N=6)
p-value
Age in years, mean (SD) 45 (15) 49.8 (11) 0.50
Female sex, n (%) 9 / 12 (75) 5 / 6 (83) 0.69
Family history of RA, n (%) 4 / 12 (33) 0 / 6 (0) 0.11
68-TJC, median (IQR) 5.0 (3–8) 5.5 (2–9) 0.87
CRP
        Elevated CRP (>10 mg/L), n (%) 5 / 12 (42) 2 / 6 (33) 0.73
        CRP-level, median (IQR) 4.7 (3–12) 4.2 (3–6) 0.32
IgM-RF level (IU/mL), mean (SD) 76.6 (77) 79.2 (64) 0.93
ACPA-level (U/mL), mean (SD) 222.8 (125) 211.0 (141) 0.87
MRI positive for inflammation
        Any inflammation present, n (%) 9 / 10 (90) 5 / 6 (83) 0.70
        Total RAMRIS score, median (IQR) 5.8 (3–19) 5.8 (4–11) 0.36

Symptoms were noted by rheumatologists as reported by the patients.

Glossary: ACPA = anti-citrullinated peptide antibody; CRP = c-reactive protein; IgM-RF = immunoglobulin M rheumatoid factor; IQR = interquartile range; MRI = magnetic resonance imaging; RA = rheumatoid arthritis; RAMRIS = Rheumatoid Arthritis MRI scoring system; SD = standard deviation; TJC = tender joint count.