Table 2.
Baseline demographics and outcome characteristics of the retrospective cohort by blood and tissue eosinophil number.
| BT-low# | T-high | B-high | BT-high | |
|---|---|---|---|---|
| Subject, n (%) | 76 (41.5) | 28 (15.3) | 22 (12.0) | 57 (31.2) |
| Male, n (%) | 50 (65.8) | 17 (60.7) | 19 (86.4) | 37 (64.9) |
| Age, mean (SD) | 35.1 (14.5) | 43.9(12.0)* | 45.5(13.2)€ | 40.2(11.1)$ |
| Weeks after surgery, median (IQR) | 84.9 (77.2) | 78.1 (50.6) | 94.3 (77.5) | 69.6 (78.9) |
| Prior sinus surgery, n (%) | 27 (35.5) | 10 (35.7) | 7 (31.8) | 13 (22.8) |
| Current smoker, n (%) | 7 (9.2) | 0 (0) | 5(22.7)$ | 6 (10.5) |
| Allergic rhinitis, n (%) | 2 (2.6) | 3 (10.7) | 2 (9.1) | 13(22.8)* |
| Asthma, n (%) | 3 (3.9) | 4 (14.3) | 2 (9.1) | 14(24.6)* |
| Preoperative L-K endoscopic score, median (IQR) | 9.0 (3.0) | 9.0 (3.25) | 8.0 (3.25) | 8.0 (4.0) |
| Preoperative L-M CT score, median (IQR) | 14.0 (6.0) | 16.0 (20.75) | 15.0 (9.0) | 17.0(9.0)$ |
| Blood eosinophil count, median (IQR) ( × 109/L) | 0.1 (0.11) | 0.18 (0.13) | 0.43(0.19)€ | 0.47(0.21)€ |
| Blood eosinophil percentage, median (IQR) (%) | 1.3 (1.6) | 1.6 (2.3) | 5.9(2.7)€ | 6.7(4.5)€ |
| Tissue eosinophil count, median (IQR) (/HPF) | 7.5 (20.75) | 77.5(164.5)€ | 8.5 (16.0) | 110.0(137.5)€ |
| Tissue eosinophil percentage, median (IQR) (%) | 2.15 (3.9) | 24.4(25.3)€ | 2.9 (4.7) | 37.2(32.8)€ |
| Post-operative TNSS, median (IQR) | 1.0 (3.0) | 1.0 (2.8) | 2.5(4.3)$ | 2.0(2.0)$ |
| Medication length>6 months after surgery, n (%) | 43 (56.6) | 12 (42.9) | 13 (59.1) | 31 (54.4) |
| Treatment outcome* | ||||
| Controlled, n (%) | 43 (56.6) | 10 (35.7) | 6 (27.3) | 15 (26.3) |
| Partly Controlled, n (%) | 21 (27.6) | 9 (32.1) | 9 (40.9) | 17 (29.8) |
| Uncontrolled, n (%) | 12 (15.8) | 9 (32.1) | 7 (31.8) | 25 (43.9) |
#Comparator group; Results in boldface indicate a P value of less than 0.05. $P < 0.05; *P < 0.01; €P < 0.001.
SD, standard deviation; IQR, interquartile range; L-K, Lund-Kennedy; L-M, Lund-Mackay; CT, computed tomography; HPF, high power field; TNSS, total nasal symptom score.