Table 2.

Model parameters

Parameter	Description	Value	Comments
τ 1	Memory-strengthening signaling time constant	0.5 h	Should be faster than memory-weakening; not affected by WT1 knockdown
τ 2	Memory-weakening signaling time constant	36 h control; 144 h WT1 knockdown	Slower than memory-strengthening, prolonged by WT1 knockdown
K1, K2	Steady-state gains	3 control; 7.2 WT1 knockdown	N/A
u	Step input magnitude	0.125 nominal Range 0.025 to 0.15 for parameter variation	Applies to all memory tests, and all animals (control or WT1 knockdown)