Table 2.

Frequencies of TYK2 alleles in childhood-onset SLE patients and healthy controls. *Corrected p value.

SNP	Position	Alleles	Minor Allele	Frequency Cases (n = 368)	Frequency Controls (n = 516)	p value*	OR 95% CI
rs12720356	10330975	A/C	C	0.007	0.023	0.041	0.308 [0.099–0.95]
rs2304256	10336652	C/A	A	0.169	0.203	0.153	0.8045 [0.596–1.085]
rs12720270	10336760	G/A	A	0.156	0.176	0.382	0.8641 [0.622–1.199]
rs280500	10351402	A/G	G	0.061	0.052	0.476	1.206 [0.719–2.022]
rs34536443	10463118	G/C	C	0.012	0.021	0.034	0.3702 [0.147–0.928]

OR values are corrected by gender and ancestry. OR = odds ratio; 95% CI = confidence interval. p < 0.05 indicates statistical significance.