. 2019 Aug 21;9:198. doi: 10.1038/s41398-019-0541-3

Table 1.

Associations between MDD presence and SASP index, sociodemographic, and clinical variables

	Current MDD (N = 527)	Controls (N = 638)	Statistics	p-value
	Mean ± SD	Mean ± SD	Statistics	p-value
SASP index	0.10 ± 1.04	−0.07 ± 0.96	t₍₁₁₆₃₎ = 2.93	0.003^a
Chronological age (years)	42.3 ± 12.4	39.9 ± 14.5	t₍₁₁₆₃₎ = 2.98	0.002
Sex
Male	178	234	X²₍₁₎ = 1.05	0.32
Female	349	404	X²₍₁₎ = 1.05	0.32
North-European ancestry
No	29	21	X²₍₁₎ = 3.43	0.08
Yes	498	617	X²₍₁₎ = 3.43	0.08
Inventory of Depressive Symptoms—30 (IDS-30)	34.7 ± 11.2	11.5 ± 9.3	t₍₁₁₆₃₎ = 38.68	<0.001
Childhood trauma (NEMESIS)	1.2 ± 1.3	0.5 ± 0.9	t₍₁₁₆₃₎ = 12.56	<0.001
Beck Anxiety Inventory (BAI)	18.8 ± 10.9	6.5 ± 7.3	t₍₁₁₆₃₎ = 23.05	<0.001
Alcohol use disorder (DSM-IV)
No	363	525	X²₍₁₎ = 28.62	<0.001
Yes	164	113	X²₍₁₎ = 28.62	<0.001
Tobacco smoking (pack/year)	12.7 ± 17.7	7.1 ± 13.2	t₍₁₁₆₃₎ = 6.21	<0.001
Mean systolic blood pressure	137.0 ± 20.2	136.2 ± 19.9	t₍₁₁₆₃₎ = 0.66	0.51
Mean diastolic blood pressure	82.5 ± 11.3	80.2 ± 11.3	t₍₁₁₆₃₎ = 3.54	<0.001
Ankle/Brachial index	1.1 ± 0.2	1.1 ± 0.1	t₍₁₁₆₃₎ = 0.79	0.42
Body Mass Index (BMI)	26.4 ± 5.7	25.1 ± 4.8	t₍₁₁₆₃₎ = 4.31	<0.001
Number of chronic diseases	1.1 ± 1.2	0.7 ± 0.9	t₍₁₁₆₃₎ = 7.07	<0.001
Physical activity (total MET/minutes a week)	3,401.8 ± 3,041.6	3,950.5 ± 3,142.3	t₍₁₁₆₃₎ = 2.68	0.004

^aAfter adjustment for potential confounding variables (age, childhood trauma, BAI scores, alcohol use disorder, tobacco smoking, diastolic blood pressure, number of chronic diseases, physical activity), there was no significant differences in the SASP index values between cMDE and controls (F_(1,1158) = 1.09, p = 0.29)