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. 2019 Aug 21;9:12184. doi: 10.1038/s41598-019-48570-x

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Molecular subtypes and administered therapy for the study cohort. (A) Proportions of subtypes from four molecular subtype signatures in the complete RNAseq cohort. (B) Subtype proportions of the AIMS-PAM50 single sample predictor for patients diagnosed 2012, 2013, and 2014 respectively, illustrating the stability of the underlying patient demographics across inclusion years. (C) Treatment proportions according to national registry data for RNAseq patients diagnosed 2012, 2013, and 2014 respectively, illustrating the stability of the underlying patient demographics during inclusion years. ACT: adjuvant chemotherapy. Endocrine: endocrine treatment.