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. 2019 Aug 21;9:12217. doi: 10.1038/s41598-019-48698-w

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Epidermal thickness and cumulative protein removal. (a) Epidermal thickness (µm) assessed before tape stripping (T0), after 5 tape strips (T5), after 15 tape strips (T15) and after 35 tape strips (T35). A significant reduction in epidermal thickness was found from T0 to T35. (b) Cumulative protein removed (µg/cm²) assessed after 5 tape strips (T5), after 15 tape strips (T15) and after 35 tape strips (T35). Assessment was performed on non-lesional skin of healthy volunteers on the volar side of the forearm.