Figure 1.

The 3D model of human FPR1. (a) The N-terminal region is reported in magenta whereas the C-terminal region in blue. For the trans-membrane region, we report the helices in red, the membrane boundaries in grey and the loop segments in green. (b) FPR1 with the binding pocket in which positive and negative charged residues are reported in blue and grey, respectively, whereas aromatic residues are reported in yellow. (c) Snapshot of the binding pocket, using the same orientation of (b), in which positive and negative charged residues are reported in blue and grey, respectively, whereas aromatic residues are reported in yellow.