Table 3.
Predictors of psoriasis relapse after withdrawal of biologics
| Estimated coefficients | Standard error | 95% CI | p value | |
|---|---|---|---|---|
| Body weight | − 0.001 | 0.0041 | − 0.009, 0.007 | 0.783 |
| Baseline PASI | − 0.150 | 0.0388 | − 0.226, − 0.074 | < 0.001 |
| Baseline PsA | ||||
| Yes | 0.074 | 0.1597 | − 0.239, 0.387 | 0.642 |
| No | Reference group | |||
| PASI improvement during treatment | 0.133 | 0.0364 | 0.062, 0.204 | < 0.001 |
| Biologic naive | ||||
| Yes | 0.610 | 0.2026 | 0.213, 1.007 | < 0.001 |
| No | Reference group | |||
| Early biologic intervention | ||||
| Yes | 0.751 | 0.1503 | 0.457, 1.046 | 0.003 |
| No | Reference group | |||
Predicting factors demonstrated by GEE multivariant analysis were baseline PASI (p < 0.001), PASI improvement during treatment (p < 0.001), biologic naivety (p < 0.001), and early biologic intervention (p = 0.003) after correcting the covariates including age, sex, body weight and PsA at baseline
PASI psoriasis area and severity index, PsA psoriatic arthritis