Table 4.

Relapse-free duration after biologics cessation (months)

	Mean	Standard error	95% CI
Pooled	7.635	1.501	4.693, 10.578
Biologic intervention (p = 0.002)
Early (n = 33)	23.864	8.167	7.855, 39.872
Delayed (n = 62)	5.355	0.824	3.740, 6.970
Biologic naivety (p < 0.001)
Naive (n = 69)	17.634	5.033	7.769, 27.499
Experienced (n = 26)	3.260	0.614	2.055, 4.464
PASI improvement (p = 0.006)
PASI 90 (n = 47)	15.505	4.619	6.452, 24.558
PASI 75 (n = 48)	11.172	4.823	1.719, 20.625
Speed to achieve PASI 75 (p = 0.250)
≤ 12 weeks (n = 64)	17.900	5.410	7.297, 28.503
> 12 weeks (n = 31)	6.258	1.431	3.453, 9.064

PASI 75 patients were grouped according to timing of biologic intervention, biologic naivety, and PASI improvement during trial. Early biologic intervention (p = 0.002), biologic naivety (p < 0.001), and PASI 90 (p = 0.006) were associated with higher relapse-free rates with Kaplan–Meier survival analysis. p values were calculated using Log rank test

PASI psoriasis area and severity index