Table II.
General characteristics and clinicals of the individuals.
| Variables | AL 69 (100) | Controls 66 (100) | P-value |
|---|---|---|---|
| Age (years, mean ± SD) | 7.8±4.8 | 9.6±5.2 | 0.019 |
| No. of leukocytes/mm3 at diagnosis | 15,000 (5,300–53,550) | 8,000 (7,000–10,000) | 0.005 |
| Sex | |||
| Female | 27 (39.1) | 27 (40.9) | 0.727 |
| Male | 42 (60.87) | 39 (59.1) | |
| Status of individuals | |||
| Alive | 18 (26.1) | 66 (100) | |
| Deceased | 51 (73.9) | – | |
| Type of acute leukemia | |||
| Lymphoblastic | 50 (72.5) | – | |
| Myeloblastic | 19 (27.5) | – | |
| Risk by age and leukocytes at diagnosis | |||
| Low-risk | 27 (39.1) | – | |
| High-risk | 42 (60.9) | – | |
| Relapse | |||
| No | 18 (26.1) | – | |
| Yes | 51 (73.9) | – | |
| Inmunophenotype | |||
| B-lineage | 46 (66.7) | – | |
| T-lineage | 1 (1.5) | – | |
| B/T-lineage | 3 (4.3) | – | |
| Myeloid-lineage | 19 (27.5) | – | |
| Chromosomal translocation | |||
| BCR-ABL [t(9;22)] | 2 (2.9) | – | |
| ETV6-RUNX1 [t(12;21)] | 1 (1.5) | ||
| AML1-ETO [t(8;21)] | 2 (2.9) | ||
| None | 57 (82.6) | – | |
| Not determined | 7 (10.1) | – |