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. 2019 Jul 22;18(3):3003–3016. doi: 10.3892/ol.2019.10642

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Copyright: © Dong et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Correlations between NDRG1 and EMT-associated markers using Pearson's correlation. (A) NDRG1 and CDH1 were positively correlated in HER2-normal samples. Results were derived from TCGA database. (B) NDRG1 and CDH1 were positively correlated in HER2-amplified samples, and NDRG1 and vimentin, and NDRG1 and fibronectin 1 were negatively correlated in HER2-amplified samples. Results were derived from TCGA database. Correlations between NDRG1 and EMT-associated markers using Pearson's correlation. (C) NDRG1 and Twist1 were negatively correlated at the protein level. (D) NDRG1 and Snail were negatively correlated at the protein level. (E) NDRG1 and vimentin were negatively correlated at the protein level. (F) NDRG1 and E-cadherin were positively correlated at the protein level. NDRG1, N-myc downstream regulated gene 1; EMT, epithelial-mesenchymal transition; HER2, human epidermal growth factor receptor 2; E-cadherin, epithelial-cadherin; CDH1, E-cadherin; FN1, fibronectin 1.

Figure 5. — Correlations between NDRG1 and EMT-associated markers using Pearson's correlation. (A) NDRG1 and CDH1 were positively correlated in HER2-normal samples. Results were derived from TCGA database. (B) NDRG1 and CDH1 were positively correlated in HER2-amplified samples, and NDRG1 and vimentin, and NDRG1 and fibronectin 1 were negatively correlated in HER2-amplified samples. Results were derived from TCGA database. Correlations between NDRG1 and EMT-associated markers using Pearson's correlation. (C) NDRG1 and Twist1 were negatively correlated at the protein level. (D) NDRG1 and Snail were negatively correlated at the protein level. (E) NDRG1 and vimentin were negatively correlated at the protein level. (F) NDRG1 and E-cadherin were positively correlated at the protein level. NDRG1, N-myc downstream regulated gene 1; EMT, epithelial-mesenchymal transition; HER2, human epidermal growth factor receptor 2; E-cadherin, epithelial-cadherin; CDH1, E-cadherin; FN1, fibronectin 1.