Table II.
Tissue samples | Tissue samples | |||||||
---|---|---|---|---|---|---|---|---|
Variable | NDRG1 (n=125) | Non-NDRG1 (n=103) | χ2 | P-value | VM (n=65) | Non-VM (n=163) | χ2 | P-value |
Age, years | 0.469 | 0.507 | 3.050 | 0.105 | ||||
<60 | 55 | 50 | 24 | 81 | ||||
≥60 | 70 | 53 | 41 | 82 | ||||
Sex | 0.534 | 0.465 | 0.941 | 0.352 | ||||
Male | 87 | 67 | 47 | 107 | ||||
Female | 38 | 36 | 18 | 56 | ||||
Tumor size, cm3 | 0.408 | 0.523 | 0.165 | 0.767 | ||||
<3 | 55 | 41 | 26 | 70 | ||||
≥3 | 70 | 62 | 39 | 93 | ||||
Histological differentiation | 8.353 | 0.005 | 4.660 | 0.040 | ||||
I/II | 75 | 42 | 26 | 91 | ||||
III/IV | 50 | 61 | 39 | 72 | ||||
TNM stage | 8.289 | 0.005 | 15.317 | <0.0001 | ||||
I/II | 65 | 34 | 15 | 84 | ||||
III/IV | 60 | 69 | 50 | 79 | ||||
Lauren type | 4.080 | 0.046 | 5.635 | 0.018 | ||||
Intestinal | 75 | 48 | 27 | 96 | ||||
Diffuse | 50 | 55 | 38 | 67 | ||||
Lymphatic metastasis | 26.784 | <0.0001 | 11.018 | 0.001 | ||||
Positive | 65 | 87 | 54 | 98 | ||||
Negative | 60 | 16 | 11 | 65 | ||||
Distant metastasis | 6.981 | 0.008 | 5.553 | 0.018 | ||||
Positive | 37 | 48 | 32 | 53 | ||||
Negative | 88 | 55 | 33 | 110 | ||||
Metastasis and recurrence | 11.255 | 0.001 | 17.137 | <0.0001 | ||||
Positive | 45 | 60 | 44 | 61 | ||||
Negative | 80 | 43 | 21 | 102 | ||||
HER2 | 6.826 | 0.032 | 10.320 | 0.005 | ||||
0/1+ | 110 | 77 | 45 | 142 | ||||
2+ | 9 | 17 | 12 | 14 | ||||
3+ | 6 | 9 | 8 | 7 |
NDRG1, N-myc downstream regulated gene 1; VM, vasculogenic mimicry; TNM, Tumor-Node-Metastasis; HER2, human epidermal growth factor 2.