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. 2019 Jul 25;18(3):3195–3201. doi: 10.3892/ol.2019.10662

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Copyright: © Du et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Effects of shikonin and paclitaxel on esophageal squamous cell carcinoma cell growth. KYSE270 cell growth inhibition was determined 48 h following treatment with increasing doses of (A) shikonin, (B) paclitaxel or a combination of shikonin (1 µM) and paclitaxel by MTT assay. Data were analyzed by Student's t-test. **P<0.001. (C) KYSE270 and (D) KYSE150 cell growth at different time points following indicated treatment as measured by the MTT assay. Data were analyzed by one-way ANOVA with Bonferroni's correction, and presented as the mean ± standard error or the mean from three independent experiments. **P<0.001 vs. PAX (100 µM) + SHK (1 mM). PAX, paclitaxel; SHK, shikonin; OD, optical density.