Table II.
Associations between prognostic factors and ADC measurements for patients with malignant breast lesions (n=307).
| ADCmax, ×10−3 mm2/s | ADCmean, ×10−3 mm2/s | ||||
|---|---|---|---|---|---|
| Prognostic factors | No. of cases | Mean ± SD | P value | Mean ± SD | P value |
| Histological Grade | <0.001 | <0.001 | |||
| 1 | 153 | 1.79±0.12 | 1.20±0.12 | ||
| 2+3 | 154 | 1.48±0.11 | 0.83±0.11 | ||
| Nuclear grade | <0.001 | <0.001 | |||
| 1 | 160 | 1.85±0.09 | 1.18±0.12 | ||
| 2+3 | 147 | 1.56±0.11 | 0.87±0.08 | ||
| Lymph node status | <0.001 | <0.001 | |||
| Positive | 148 | 1.56±0.11 | 0.88±0.09 | ||
| Negative | 159 | 1.85±0.09 | 1.17±0.12 | ||
| ER | <0.001 | <0.001 | |||
| Positive | 91 | 1.80±0.15 | 1.14±0.17 | ||
| Negative | 216 | 1.67±0.17 | 0.99±0.17 | ||
| PR | 0.006 | <0.001 | |||
| Positive | 67 | 1.76±0.18 | 1.13±0.21 | ||
| Negative | 240 | 1.69±0.17 | 1.00±0.17 | ||
| HER-2 | <0.001 | <0.001 | |||
| Positive | 178 | 1.82±0.12 | 1.14±0.15 | ||
| Negative | 129 | 1.56±0.12 | 0.88±0.09 | ||
| Ki-67 | <0.001 | <0.001 | |||
| <14% | 103 | 1.89±0.08 | 1.24±0.10 | ||
| ≥14% | 204 | 1.62±0.13 | 0.92±0.11 | ||
ADC, apparent diffusion coefficient; SD, standard deviation; ER, estrogen receptor; PR, progesterone receptor; HER-2, human epidermal growth factor 2; Ki-67, proliferation marker protein Ki-67.