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. 2019 May 8;37(3):296–312. doi: 10.5534/wjmh.190055

Table 3. Antioxidant classification in relation to its action on sperm characteristics.

Type Function References
Enzymatic:
 Superoxide dismutase First line defense antioxidants [94,95]
 Catalase First line defense antioxidants [54,96]
 Glutathione peroxidase Scavenges lipid peroxides and hydrogen peroxide [97,98]
 Glutathione reductase Scavenges lipid peroxides and hydrogen peroxide [99]
Non enzymatic:
 Vitamin C Neutralizes free radicals [100,101]
 Vitamin E Neutralizes free radicals [102,103]
 Ferritin and carnitines Neutralizes free radicals and acts as an energy source [126]
 Coenzyme Q10 In its reduced form, scavenges free radicals intermediate in mitochondrial electron transport system [104]
 Transferrin Sperm vitality, DNA integrity and OS homeostasis [105]
 Zinc Formation of free oxygen radicals and sperm chromatin stability [106]
 Selenium Sperm motility and OS homeostasis [107]
 N-acetyl L-cysteine Free radical scavenging activity [108,109]
 L-arginine Formation of free oxygen radicals [110]
 Folic acid Sperm DNA integrity [111]

OS: oxidative stress.