Table I.

GO Enrichment analysis of upregulated DEGs.

A, Biological processes
GO ID	Pathway description	Gene count	FDR
GO.0006807	Nitrogen compound metabolic process	562	5.32×10−57
GO.0034641	Cellular nitrogen compound metabolic process	537	4.68×10−56
GO.0044237	Cellular metabolic process	712	4.33×10−50
GO.0044238	Primary metabolic process	719	4.33×10−50
GO.0071704	Organic substance metabolic process	722	7.52×10−47
B, Molecular function
GO ID	Pathway description	Gene count	FDR
GO.000723	RNA binding	292	3.36×10−75
GO.0044822	Poly(A) RNA binding	249	1.00×10−73
GO.0003676	Nucleic acid binding	410	2.01×10−40
GO.1901363	Heterocyclic compound binding	520	1.27×10−36
GO.0097159	Organic cyclic compound binding	523	4.32×10−36
C, Component function
GO ID	Pathway description	Gene count	FDR
GO.0044446	Intracellular organelle part	759	5.24×10−84
GO.0031974	Membrane-enclosed lumen	527	1.44×10−81
GO.0044422	Organelle part	764	1.44×10−81
GO.0070013	Intracellular organelle lumen	516	9.85×10−81
GO.0043233	Organelle lumen	519	7.00×10−80

GO, Gene Ontology; DEGs, differentially expressed genes; FDR, false discovery rate.