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. 2019 Jul 22;18(3):2891–2896. doi: 10.3892/ol.2019.10649

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Copyright: © Hao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Various concentrations of matrine affect the expression of PI3K/AKT pathway-associated proteins in THP-1 cells. Western blotting was performed in triplicate. Matrine decreased the expression levels of p-PI3K, p-Akt and p-mTOR in a concentration-dependent manner. However, no differences were revealed in the expression levels of PI3K, Akt and mTOR following treatment with matrine. PI3K, phosphoinositide 3-kinase; Akt, protein kinase B; mTOR, mechanistic target of rapamycin kinase; p, phosphorylated.