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. 2019 Jul 25;18(3):3256–3264. doi: 10.3892/ol.2019.10664

Table II.

Genetic features of human colon cancer cells.

Cell line KRAS BRAF PIK3CA PTEN TP53
HT-29 wt V600E P449T wt R273H
Caco-2 wt wt wt wt E204X
DLD-1 G13D wt E545K, D549N wt S241H
HCT116 G13D wt H1047R wt wt

KRAS, GTPase KRas; BRAF, serine/threonine-protein kinase B-raf; PIK3CA, phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit α isoform; PTEN, phosphatase and tensin homolog; TP53, cellular tumor antigen p53; wt, wild-type.