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. 2019 Aug 22;7(5):e00511. doi: 10.1002/prp2.511

Figure 2.

Figure 2

Core analog synthesis and structure overview (A) Synthetic routes to all analogs (R′ = Me for U‐ & US‐series, R′ = H for Udes‐series): (a) KCN, Me2NH.HCl, H2O, rt, 16 hour; (b) LiAlH4, Et2O, rt, 16 hour; (c) Et3N, RCOCl, Et2O, rt, 16 hour. US starts with the (1S,2S) diamine. (B) General structures of the analogs in the four series tested: A, U, Udes, and US