Table 1.
Classifier | Accuracy | Sensitivity | Specificity | Precision | Area under the precision-recall curve | Area under the ROC curve |
---|---|---|---|---|---|---|
Our classifier | 0.9972 | 0.9898 | 0.9989 | 0.9952 | 0.9996 | 0.9999 |
COME | 0.9285 | 0.9639 | 0.9202 | 0.7391 | 0.9965 | 0.9859 |
CPAT | 0.8661 | 0.9624 | 0.8436 | 0.5905 | 0.9906 | 0.9620 |
CPC | 0.7487 | 0.9865 | 0.6930 | 0.4296 | 0.9895 | 0.9585 |
HMMER | — | — | — | — | 0.9842 | 0.9326 |
lncScore | 0.9374 | 0.9463 | 0.9353 | 0.7742 | 0.9949 | 0.9808 |
PhyloCSF | 0.6079 | 0.8675 | 0.5471 | 0.4566 | 0.9689 | 0.8891 |
PLEK | 0.7120 | 0.9069 | 0.6664 | 0.5446 | 0.9640 | 0.8586 |
For the computation of each performance metric, we considered lncRNAs as the positive class and coding transcripts as the negative class.