Table 3.
Clinical Characteristics of Study Participants by KDIGO GFR Categories.
| G3a-G3b (N = 147) | G4 (N = 166) | G5 (N = 61) | P value | |
|---|---|---|---|---|
| Hip BMD (Mean, SD) | 0.95 (0.18) | 0.92 (0.16) | 0.86 (0.14) | .0008 |
| Hip BMD T-Score | −0.82 (1.24) | −1.08 (1.09) | −1.49 (0.93) | .0011 |
| Hip BMD Z-Score | 0.09 (1.22) | −0.04 (1.06) | −0.59 (0.97) | .0006 |
| Baseline fractures, No. (%) | 57 (38.8) | 57 (34.3) | 29 (47.5) | .1899 |
| Incident fractures, No. (%) | 21 (14.3) | 26 (15.7) | 12 (19.7) | .6237 |
| Calcium (Mean, SD), mmol/L | 2.35 (0.14) | 2.30 (0.15) | 2.23 (0.17) | <.0001 |
| Phosphorus (Mean, SD), mmol/L | 1.16 (0.24) | 1.27 (0.26) | 1.54 (0.45) | <.0001 |
| ALP (Median, IQR), U/L | 86 (70-108) | 88 (73-113.5) | 90 (72-109) | .8444 |
| PTH (Median, IQR), pmol/L | 6.7 (4.3-10.3) | 11.7 (7.8-16.5) | 20.1 (11.6-29.8) | <.0001 |
| eGFR (Mean, SD) | 41.0 (8.5) | 22.8 (4.2) | 10.8 (4.0) | <.0001 |
Note. Continuous variables given as mean (standard deviation) for normally distributed variables and median (interquartile range) for non-normally distributed variables. Categorical variables presented as No. (%). KDIGO = Kidney Disease Improving Global Outcomes; GFR = Glomerular Filtration Rate; BMD = bone mineral density; ALP: alkaline phosphatase; IQR: interquartile range; PTH = parathyroid hormone.