Supplementary Fig. 2.

IPA analysis in nerve reveals pathways pertaining ion channel localization and protective response to oxidative stress. Interaction networks generated using IPA software showing proteins which were consistently down (green) or up (red) regulated in sciatic nerve between P12 and P24 arranged by known interactions. Intensity of colour reflects magnitude of change. White represents a molecule that is absent from the datasets but an important component of the network. Solid connecting lines represent a direct interaction, while dashed connecting lines indicate an indirect interaction. Note enrichment of proteins pertaining to ion channel localization and the protective response to oxidative stress.