. Author manuscript; available in PMC: 2020 Sep 1.

Published in final edited form as: J Mol Cell Cardiol. 2019 Jul 21;134:144–153. doi: 10.1016/j.yjmcc.2019.07.007

Table 1.

Initial conditions for tcaCALC modeling. Subsequent optimization of the values is accomplished by a Levenberg-Marquardt gradient-descent algorithm. Fractional CHO is the initial estimate of the carbohydrate versus non-carbohydrate sources of acetyl-CoA.

Pathway	ModYPC	ModYS-YPC
Ketone	0.34	0.34
Fatty acid	0.17	0.17
[3-¹³C]lactate fraction	0.9	0.9
Fractional CHO	0.4	0.4
Y_PC	0.1	0.1
Y_s	n/a	0.1