Table 2.

List of potential covariates and factors (partial list)

Factor or covariate	Type	Defined as
Treatment	Factor	SGLT2 inhibitor, diet, CRT
GLP1 agonists	Factor	Yes, no
Baseline body weight/ BMI	Covariate	–
HbA1c (%)	Covariate	–
Caloric consumption (Kcal)	Covariate	–
Resting metabolic rate (Kcal)	Covariate	–
Body fat %	Covariate	–
Strength (kg)	Covariate	–
Frailty or sarcopenia status	Factor	Frail or sarcopenic, pre-frail or pre sarcopenic and robust

Abbreviations: BMI Body Mass Index, CRT Circuit Resistance Training, GLP-1 Glucagon-Like Peptide-1, HbA1c Hemoglobin A1C