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. 2019 Jul 26;18(3):2187–2193. doi: 10.3892/etm.2019.7814

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Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Treg and Th17 cell counts in patients with TSCC. Gating criteria was used to define the CD4+ T cell population and the CD4+/CD25+/Foxp3+ Treg cells were identified. Different cell subsets were distinguished according to different cell labels: Treg cells, CD4+/CD25+/Foxp3+; and Th17 cells, CD4+/L-17a+ cells. (A) Flow cytometry plots and quantification of CD4+T cells, (B) CD4+/CD25+/Foxp3+ Treg cells and (C) CD4+/IL-17a+ cells. Each point represents a patient with TSCC or a healthy person. *P<0.05 vs. control group; ^#P<0.05 vs. TSCC stage I + II. TSCC, tongue squamous cell carcinoma; Treg, regulatory T helper cell; Th17, T helper cell 17; CD, cluster of differentiation; Foxp3, forkhead box protein 3; SSC, side scatter.

Figure 2. — Treg and Th17 cell counts in patients with TSCC. Gating criteria was used to define the CD4+ T cell population and the CD4+/CD25+/Foxp3+ Treg cells were identified. Different cell subsets were distinguished according to different cell labels: Treg cells, CD4+/CD25+/Foxp3+; and Th17 cells, CD4+/L-17a+ cells. (A) Flow cytometry plots and quantification of CD4+T cells, (B) CD4+/CD25+/Foxp3+ Treg cells and (C) CD4+/IL-17a+ cells. Each point represents a patient with TSCC or a healthy person. *P<0.05 vs. control group; ^#P<0.05 vs. TSCC stage I + II. TSCC, tongue squamous cell carcinoma; Treg, regulatory T helper cell; Th17, T helper cell 17; CD, cluster of differentiation; Foxp3, forkhead box protein 3; SSC, side scatter.