Figure 1.
No changes in white blood cells, hemoglobin, and platelets counts of Sirt1Δ/Δ mice. (A) White blood cell counts, lymphocytes, neutrophil, monocytes, hemoglobin and platelet measurements from mice of the indicated genotype (n=4–5). (B) Reverse transcription-quantitative PCR analysis of Sirt1 expression in CD31−CD45−Ter119− Sirt1Δ/Δ bone marrow cells (n=3). Data are presented as mean + SEM. *P<0.05. n.s., not significant; Sirt1, sirtuin 1; Sirt1Δ/Δ, sirtuin 1 conditional knockout; WBC; white blood cells; LY, lymphocytes; NEU, neutrophils; MO, monocytes; HGB, hemoglobin; PLT, platelet; CD, cluster of differentiation.