Fig. 2.

Parkin KO mice show protection against ethanol-induced hepatic lipid accumulation. a Liver sections of pair- or ethanol-fed WT mice and parkin KO mice were stained with hematoxylin and eosin (H&E) and Oil red O (Scale bars, 50 μm). b Expression of genes involved in lipogenesis (SREBP-1c and CD36) and lipid oxidation (AOX and MCAD) in the livers of pair- or ethanol-fed WT mice and parkin KO mice. n = 10 per group; means ± SD; ^*P < 0.05, pair-fed WT mice versus ethanol-fed WT mice; ^#P < 0.05, ethanol-fed WT mice versus ethanol-fed parkin KO mice