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. 2019 Aug 22;20:433. doi: 10.1186/s12859-019-2994-z

Fig. 1.

Fig. 1

Lineage tree representation of cells of the immune system. Immune cells are derived from hematopoietic stem cells (HSCs). HSCs differentiate into lymphoid and myeloid progenitors that further branch out to the more specific cell types associated with adaptive and innate immunity. This Figure indicates the main immune cell subsets and arrows are to show lineage relationships. Gene signatures were developed in this study for immune cells highlighted in bold