Table 3.
HRQoL (EORTC QLQ-C30) | Young adult patients (N = 179) | Older adult patients (N = 200) | Group differences | Effect size | mean differences – clinical relevance* | |||
---|---|---|---|---|---|---|---|---|
Mean | SD | Mean | SD | p | d | |||
Function scales | ||||||||
Physical Function | 79.59 | (18.06) | 67.73 | (27.79) | <.001 | .516 | 11.86 | small |
Role Function | 64.25 | (26.33) | 60.75 | (36.64) | .292 | .11 | 3.50 | trivial |
Emotional Function | 59.50 | (27.71) | 78.04 | (20.70) | <.001 | .76 | −18.54 | – |
Cognitive Function | 69.46 | (25.08) | 80.25 | (22.48) | <.001 | .45 | −10.79 | medium |
Social Function | 57.45 | (32.77) | 74.75 | (31.88) | <.001 | .54 | −17.30 | large |
Symptom scales | ||||||||
Fatigue | 46.99 | (25.06) | 43.72 | (31.21) | .265 | .12 | 3.27 | trivial |
Nausea/vomiting | 7.08 | (16.27) | 7.25 | (17.17) | .920 | .00 | −0.17 | trivial |
Pain | 22.63 | (27.46) | 34.00 | (33.91) | <.001 | .34 | −11.37 | small |
Single items | ||||||||
Dyspnoea | 24.58 | (29.63) | 25.67 | (33.70) | .741 | .03 | −1.09 | trivial |
Insomnia | 35.01 | (34.49) | 34.00 | (38.39) | .789 | .03 | 1.01 | trivial |
Appetite loss | 13.22 | (23.55) | 21.17 | (33.61) | .009 | .27 | −7.95 | small |
Constipation | 5.40 | (15.86) | 15.00 | (28.11) | <.001 | .42 | −9.60 | small |
Diarrhoea | 14.15 | (25.20) | 9.33 | (22.46) | .050 | .20 | 4.82 | small |
Financial difficulties | 44.13 | (37.33) | 7.50 | (20.17) | <.001 | 1.22 | 36.63 | medium |
Global quality of life | 68.39 | (17.84) | 58.50 | (22.28) | <.001 | .49 | 9.89 | small |
SD Standard deviation, EORTC QLQ-C30 European Organisation for the Research and Treatment of Cancer Quality of Life Questionnaire -
Core 30, * = by Cocks et al. (2011)