Fig. 2.

MiR-6778-5p promotes the proliferation of CRC cells. a MiR-6778-5p level was analyzed by real-time PCR after transfection with miRNA mimic. b Representative image of colony formation capacity. Cell colony number was analyzed from three replicate experiments. c Viability of HCT116, HT29 and SW620 cells was measured using CCK-8 assay at 24 h, 36 h, 48 h and 72 h after transfection with miRNA mimic or inhibitor. d Analysis of DNA synthesis of HCT116 cells transfected with miR-6778 mimic or inhibitor by EdU assay. Bars, 100 μm. Data are represented as mean ± SD. *P < 0.05, **P < 0.01 versus the control group