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. 2012 Oct 24;32(43):14885–14898. doi: 10.1523/JNEUROSCI.2849-12.2012

Figure 8.

Figure 8.

Normal learning in young adult and intermediate-age TrkaNesCre mice submitted to passive avoidance and contextual and cued fear conditioning tasks. A, B, No significant difference in the step-through latencies in the passive avoidance apparatus both before (Training) and 24 h after footshock (Test; training, F(1,32) = 1.15, p > 0.05; test, F(1,32) = 0.26, p > 0.05) were observed in TrkaNesCre and control mice at 3–4 months (3–4M) of age (training, F(1,32) = 1.15, p > 0.05; test, F(1,32) = 0.26, p > 0.05) or at 11 months (11M; training, F(1,25) = 0.32, p > 0.05; test, F(1,25) = 0.30, p > 0.05). C–F, No significant differences were observed when TrkaNesCre and age-matched control mice were compared for the percentage of freezing recorded during the training before footshock presentation (Untrained) and 24 h after training, both with CTX (3–4 months old, F(1,11) = 1.25, p > 0.05; 11 months old, F(1,18) = 0.72, p > 0.05) and in a different context (Pre-CS) with tone presentation (CS, cued memory; Pre-CS, 3–4 months old, F(1,11) = 0.2, p > 0.05; 11 months old, F(1,18) = 0.34, p > 0.05) or during tone presentation (CS, 3–4 months old, F(1,11) = 0.11, p > 0.05; 11 months old, F(1,18) = 3.01, p > 0.05).