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. 2013 Jan 16;33(3):1068–1087. doi: 10.1523/JNEUROSCI.3396-12.2013

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Copyright © 2013 the authors 0270-6474/13/331068-20$15.00/0

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Figure 13. — The GLAST inhibition exerted by UCPH-101 is an intramolecular event. A, The potential GLAST trimer combinations formed in cell populations transfected with four different pairwise combinations of WT GLAST, GLAST-G120L, GLAST-R479T, and GLAST-G120L/R479T cDNAs. B, Concentration-inhibition curves for Glu, TBOA, and UCPH-101 at tsA201 cells transfected with different combinations of WT GLAST, GLAST-G120L, GLAST-R479T, and GLAST-G120L/R479T cDNAs (1:1 transfection ratios) in the [³H]-d-Asp uptake assay (n = 4).