Figure 8.

Firing rate analysis between the intertic and tic period. A, Comparison of striatal single-cell activity associated with LFP spikes in the intertic (black trace and raster) and tic (red trace and raster) interval. Data are aligned with striatal LFP spike onset. Note the preservation of the response during the intertic interval. B, An example of spiking activity from the GPe between the two states. Note the partial preservation of the response during the intertic interval, with the early inhibitory peak maintained and the later excitatory peak reduced. C, The preservation of response in the GPi between the two intervals. D, Differential M1 activity between the intertic and tic intervals. E, Differential CbllCx activity between the two intervals. F, Differential dentate nucleus activity between the two intervals.