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. 2013 Jan 9;33(2):595–610. doi: 10.1523/JNEUROSCI.2583-12.2013

Figure 7.

Figure 7.

NHE6 significantly overlaps with AMPAR subunit GluA1 in dendrites and dendritic spines of primary hippocampal neurons. Representative confocal micrographs show immunofluorescent localization of NHE6 and GluA1 and their colocalization in mouse primary hippocampal neurons (14+ DIV). NHE6 andGluA1 partially colocalize in dendrites and at dendritic spines, but they are found to be significantly overlapping with one another by the Mander's coefficient (NHE6:GluA1, 0.7916; GluA1:NHE6, 0.845; p < 0.05). Magnification in all panels is identical. Scale bar, 2 μm. White dashed line denotes secondary dendrite of an mGFP-positive dendrite.