Table 1.

eWM training task-demand-related activation at pre-training^a

Brain region	L/R	Cluster size (voxels)	Maxima of cluster x/y/z (mm)b	Z
Activation increasec
Superior frontal gyrus	R	55	24/57/03	3.56
Middle frontal gyrus	L	125	−30/51/12	4.68
	R	1216	27/15/51	4.80
	R	1216	27/09/60	4.74
Inferior frontal gyrus	L	43	−39/21/27	3.67
Supplementary motor area/middle cingulate	L	1216	−06/18/45	4.73
Middle orbitofrontal gyrus	R	55	27/51/−12	3.66
Inferior parietal lobe	R	1671	42/−36/42	5.45
Precuneus	R	1671	−09/−57/51	5.10
Inferior temporal gyrus	R	64	51/−57/−09	4.33
Middle posterior insula	R	18	30/24/−03	3.16
Globus pallidus	L	13	−15/00/−03	3.10
Caudate	L	40	−12/06/12	2.96
Cerebellum	L	266	−12/−54/−45	4.59
	L	266	−36/−66/−48	3.90
	R	224	36/−54/−36	4.53
	R	224	33/−63/−51	3.89
	R	14	12/−54/−48	3.58
Activation decreased
Medial prefrontal cortex (medial superior frontal gyrus)	R	759	09/57/21	4.58
	R	13	09/33/54	2.92
	R	11	12/42/42	2.77
	R	11	06/45/48	2.53
Subgenual prefrontal cortex	R	759	00/42/−18	4.32
Rolandic operculum	L	3856	−48/−24/18	6.11
	R	1988	51/−21/18	5.47
Precentral gyrus	R	45	21/−27/63	3.63
Superior temporal gyrus	R	97	60/−57/24	3.35
Temporoparietal junction	L	142	−45/−63/24	3.63
Middle temporal gyrus	R	97	60/−60/09	3.87
	R	97	54/−51/06	2.87
Fusiform gyrus	R	19	39/−33/−18	3.64
Amygdala/hippocampus	L	3856	−27/−06/−15	5.86
	R	1988	27/−06/−15	4.99
Parahippocampal region	R	88	12/−39/−06	3.04
Insula	L	3856	−39/−06/−06	5.85
	R	1988	39/−03/−09	4.84
Thalamus	L	13	−12/−24/03	2.74
Cuneus	L	17	−03/−84/30	2.66
	R	8	09/−87/36	2.67
Lingual gyrus	L	8	−12/−51/−03	2.62
	R	88	15/−48/−09	3.01
Cerebellum	L	43	−30/−81/−36	3.85
	R	29	33/−78/−36	3.20
	R	88	18/−54/−18	3.18

^aRegions that showed differential activation at n-back = 3 compared with n-back = 1 back on the scanner version of the eWM training task at pre-training. Threshold for whole-brain correction at p_FDR < 0.05.

^bStereotaxic coordinates of peak voxels in MNI space.

^ct test contrast: Load 3 > Load 1.

^dt test contrast: Load 3 < Load 1.