Table 6.
Regions showing activation changes from pre-training to post-training during the eWM task after eWM traininga
| Brain region | L/R | Cluster | Cluster size (voxels) | Maxima of cluster x/y/z (mm)b | Z |
|---|---|---|---|---|---|
| n-back = 3 | |||||
| Dorsolateral to middle PFC | L | 6 | 182 | −33/48/3 | 3.71 |
| 6 | −30/54/21 | 3.52 | |||
| R | 2 | 1686 | 45/12/18 | 4.95 | |
| 2 | 27/48/18 | 4.39 | |||
| Middle OFC | L | 6 | −45/51/−3 | 3.49 | |
| Inferior parietal cortex | L | 3 | 260 | −57/−48/39 | 4.56 |
| 3 | −39/−57/45 | 3.24 | |||
| Middle temporal gyrus | R | 1 | 1095 | 60/−30/−9 | 5.06 |
| Inferior temporal gyrus | L | 5 | 94 | −57/−36/−15 | 3.85 |
| Fusiform gyrus | L | 7 | −42/−54/−18 | 3.07 | |
| Insula | L | 4 | −36/15/−3 | 3.88 | |
| R | 2 | 42/21/3 | 4.06 | ||
| Thalamus | L | 4 | 556 | 9/−9/18 | 3.90 |
| Inferior occipital gyrus | L | 7 | 80 | −48/−69/−9 | 3.34 |
| Cerebellum | R | 8 | 21 | 36/−57/−45 | 3.25 |
| n-back = 5 | |||||
| Lateral PFC | R | 2 | 121 | 51/27/−3 | 4.28 |
| 2 | 48/24/9 | 3.99 | |||
| 4 | 36 | 48/15/24 | 3.54 | ||
| Supplementary motor area | R | 3 | 23 | 12/21/60 | 3.74 |
| Middle cingulate | L | 5 | 7 | −6/−24/33 | 3.20 |
| Angular gyrus | L | 1 | 211 | −54/−57/36 | 4.67 |
aRegions that showed pre-training to post-training BOLD activation increases at n-back = 5 in the eWM training group. Threshold for whole-brain correction was set at pFDR < 0.05.
bStereotaxic coordinates of peak voxels in MNI space.