. 2019 Aug 19;179(11):1528–1536. doi: 10.1001/jamainternmed.2019.3007

Table 3. Clinical Outcomes Associated With Receiving an Antihypertensive Intensification Regimen at Hospital Discharge in Subgroups With Controlled and Elevated Prehospitalization Baseline Blood Pressure Subgroups^a.

Outcome	Well-Controlled Baseline Blood Pressure Group (SBP<140 mm Hg)^b				Elevated Baseline Blood Pressure Group (SBP≥140 mm Hg)^c
	No. With Event		Hazard Ratio (95% CI)	NNH (95% CI)^d	No. With Event		Hazard Ratio (95% CI)	NNH (95% CI)^d
	Intensified (n = 1122)	Not Intensified (n = 1122)	Hazard Ratio (95% CI)	NNH (95% CI)^d	Intensified (n = 878)	Not Intensified (n = 878)	Hazard Ratio (95% CI)	NNH (95% CI)^d
Hospital readmission, 30 d	252	193	1.34 (1.11-1.62)	19 (12-51)	178	161	1.12 (0.91-1.39)	NA
Serious adverse event, 30 d	70	43	1.65 (1.13-2.40)	41 (24-167)	43	36	1.19 (0.77-1.86)	NA
Cardiovascular event, 365 d	146	109	1.37 (1.08-1.75)	30 (17-147)	127	105	1.24 (0.95-1.60)	NA

Abbreviations: NA, not applicable; NNH, number needed to harm; SBP, systolic blood pressure.

^{^a}

Patients were censored at 30 or 365 days after index hospitalization discharge as indicated. Subdistribution hazards were generated from competing risk regression models, accounting for the competing risk of death. Serious adverse events were defined as first emergency department visit or hospitalization for injurious fall, syncope, hypotension, electrolyte abnormalities, or acute kidney injury. Cardiovascular events were defined as first emergency department visit or hospitalization for acute myocardial infarction, unstable angina, stroke, heart failure, or hypertension.

^{^b}

Propensity score matching and survival analyses were performed separately for this subgroup of patients in whom well-controlled prehospitalization baseline SBP was defined to include all patients with an outpatient SBP less than 140 mm Hg before index hospitalization.

^{^c}

Propensity score matching and survival analyses were performed separately for this subgroup of patients in whom elevated prehospitalization baseline SBP was defined to include all patients with an outpatient SBP of 140 mm Hg or higher before index hospitalization.

^{^d}

The NNH was only estimated when there was a statistically significant direction of treatment effect.

Table 3. Clinical Outcomes Associated With Receiving an Antihypertensive Intensification Regimen at Hospital Discharge in Subgroups With Controlled and Elevated Prehospitalization Baseline Blood Pressure Subgroupsa.

Table 3. Clinical Outcomes Associated With Receiving an Antihypertensive Intensification Regimen at Hospital Discharge in Subgroups With Controlled and Elevated Prehospitalization Baseline Blood Pressure Subgroups^a.