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Homeostatic shift in synaptic NMDAR subunit composition in response to prolonged TTX treatment. A, τw values from biexponential fits of evoked NMDAR-EPSCs recorded at +40 mV from control and TTX-treated neurons. B, Amplitude of evoked NMDAR-EPSCs (Vm = +40 mV) before (baseline) and after 10–12 min administration of the selective GluN2B-containing NMDARs antagonist ifenprodil (3 μm).
