Table 1.

Peak MNI coordinates for regions with significant mPFC resting state functional connectivity in TMD patients and healthy controls, and significantly enhanced mPFC functional connectivity in TMD patients compared with healthy controls (FWE-corrected at Z > 2.3, cluster-based threshold of p < 0.05)

Region	Z-max	Peak voxel (MNI coordinates, mm)
		x	y	z
mPFC functional connectivity
Controls
mPFC	9.0	0	58	−8
R precuneus	3.66	8	−64	36
R parahippocampal gyrus	4.5	30	−10	−34
R middle frontal gyrus	3.38	26	32	34
L parahippocampal gyrus	3.17	−34	−10	−34
R superior frontal gyrus	2.82	28	36	54
PCC	2.74	2	−14	30
L superior frontal gyrus	2.74	−4	32	62
R temporal pole	2.69	50	8	−30
Retrosplenial cortex	2.72	−8	−52	8
TMD
mPFC	7.72	−2	58	−4
L inferior parietal lobule	4.76	−38	−78	36
R inferior parietal lobule	5.12	50	−68	26
R lateral temporal cortex	4.69	60	−12	−20
L lateral temporal cortex	4.15	−64	−18	−14
Visual cortex	3.66	4	−90	2
R orbitofrontal cortex	3.98	36	32	−18
L posterior thalamus	3.65	−8	−30	−2
R parahippocampal gyrus	2.86	12	4	−20
R orbitofrontal cortex	2.55	−18	22	−22
TMD > controls
Lingual gyrus	3.74	6	−66	6
Occipital pole	3.17	−2	−88	−2
R PCC/precuneus (ventral)	3.15	22	−62	12
Precuneus (dorsal)	3.11	0	−78	42
R retrosplenial cortex	3.07	8	−50	−8

The image was thresholded at Z > 3 to obtain peak coordinates.