Table 2.
Peak MNI coordinates for regions showing a significant positive correlation between mPFC functional connectivity and pain rumination in TMD patients (FWE-corrected at Z > 2.3, cluster-based threshold of p < 0.05)
| Region | Z-max | Peak voxel (MNI coordinates, mm) |
r | p | ||
|---|---|---|---|---|---|---|
| x | y | z | ||||
| Positive correlation between mPFC FC and pain rumination in TMD | ||||||
| PCC | 3.23 | 2 | −36 | 10 | 0.70 | 0.002 |
| R medial thalamus | 3.39 | 4 | −16 | 8 | 0.75 | 0.0006 |
| L PCC/precuneus | 3.54 | −6 | −52 | 18 | 0.77 | 0.0003 |
| R medial thalamus | 3.49 | 10 | −24 | 8 | 0.71 | 0.001 |
| Midbrain | 3.6 | 2 | −30 | −2 | 0.76 | 0.0004 |
| L anterior thalamus | 3.7 | −2 | −6 | 0 | 0.75 | 0.0005 |
| R PCC/precuneus | 3.04 | 4 | −50 | 18 | 0.70 | 0.002 |
| R retrosplenial cortex | 3.13 | 6 | −52 | 8 | 0.70 | 0.002 |
| PVG/PAG | 2.55 | 2 | −30 | −6 | 0.61 | 0.009 |
The image was thresholded at Z > 3 to obtain peak coordinates (with exception of PVG/PAG where peak voxel at level of z = −6 is shown). Pearson's correlation coefficient values were extracted from voxels at listed coordinates.