Study	Reason for exclusion
Chang 1994	Does not fulfil the intervention inclusion criteria
Chen 1993	Does not fulfil the intervention inclusion criteria
Chen 1995	Does not fulfil the intervention inclusion criteria
Chen 1999	Does not fulfil the intervention inclusion criteria
Chen 2013	Does not fulfil the intervention inclusion criteria
Chen 2015	Does not fulfil the intervention inclusion criteria
Cui 2002	Does not fulfil the intervention inclusion criteria
Dai 2009	Does not fulfil the intervention inclusion criteria
Dai 2015	Does not fulfil the intervention inclusion criteria
Dong 1997	Does not fulfil the intervention inclusion criteria
Fu 1994	Does not fulfil the intervention inclusion criteria
Fu 2007	Does not fulfil the intervention inclusion criteria
Fu 2015	Does not fulfil the intervention inclusion criteria
Gao 2016	Does not fulfil the intervention inclusion criteria
Ge 2013	Does not fulfil the intervention inclusion criteria
Gu 1996	Does not fulfil the intervention inclusion criteria
Guo 2000	Does not fulfil the intervention inclusion criteria
Han 2005	Does not fulfil the intervention inclusion criteria
Han 2009	Does not fulfil the intervention inclusion criteria
Han 2012	Does not fulfil the intervention inclusion criteria
Hao 2014	Does not fulfil the intervention inclusion criteria
He 2002	Does not fulfil the intervention inclusion criteria
Huang 2005	Does not fulfil the intervention inclusion criteria
Huang 2011b	Does not fulfil the intervention inclusion criteria
Jin 2011	Does not fulfil the intervention inclusion criteria
Kong 2005	Does not fulfil the intervention inclusion criteria
Kong 2008	Does not fulfil the intervention inclusion criteria
Lan 2001	Does not fulfil the intervention inclusion criteria
Li 1990	Does not fulfil the intervention inclusion criteria
Li 1992	Does not fulfil the intervention inclusion criteria
Li 2000a	Does not fulfil the intervention inclusion criteria
Li 2000b	Not chronic hepatitis B
Li 2005	Self‐controlled clinical study
Li 2011	Not a randomised clinical trial
Li 2013	Does not fulfil the intervention inclusion criteria
Li 2014	Does not fulfil the intervention inclusion criteria
Li 2015	Does not fulfil the intervention inclusion criteria
Li 2016	Does not fulfil the intervention inclusion criteria
Lian 1990	Does not fulfil the intervention inclusion criteria
Lian 1991	Does not fulfil the intervention inclusion criteria
Lin 2003	Does not fulfil the intervention inclusion criteria
Lin 2003b	Does not fulfil the intervention inclusion criteria
Lin 2011	Does not fulfil the intervention inclusion criteria
Liu 1999	Does not fulfil the intervention inclusion criteria
Liu 2003	Does not fulfil the intervention inclusion criteria
Liu 2003b	Does not fulfil the intervention inclusion criteria
Liu 2004	Does not fulfil the intervention inclusion criteria
Liu 2004b	Does not fulfil the intervention inclusion criteria
Liu 2005	Does not fulfil the intervention inclusion criteria
Liu 2006	Does not fulfil the intervention inclusion criteria
Lu 2004	Does not fulfil the intervention inclusion criteria
Lu 2004b	Does not fulfil the intervention inclusion criteria
Lu 2011	Does not fulfil the intervention inclusion criteria
Ma 2002	Does not fulfil the intervention inclusion criteria
Ma 2014	Does not fulfil the intervention inclusion criteria
Qin 2009	Does not fulfil the intervention inclusion criteria
Qiu 2006	Does not fulfil the intervention inclusion criteria
Ruan 2004	Does not fulfil the intervention inclusion criteria
Shao 2011	Does not fulfil the intervention inclusion criteria
Shi 1997	Does not fulfil the intervention inclusion criteria
Song 2008	Does not fulfil the intervention inclusion criteria
Sun 2000	Does not fulfil the intervention inclusion criteria
Sun 2003	Does not fulfil the intervention inclusion criteria
Tang 2007	Does not fulfil the intervention inclusion criteria
Tang 2013	Does not fulfil the intervention inclusion criteria
Tao 1988	Does not fulfil the intervention inclusion criteria
Tian 1998	Does not fulfil the intervention inclusion criteria
Tian 2005	Does not fulfil the intervention inclusion criteria
Wang 1990	Does not fulfil the intervention inclusion criteria
Wang 1993	Does not fulfil the intervention inclusion criteria
Wang 2003	Does not fulfil the intervention inclusion criteria
Wang 2010	Does not fulfil the intervention inclusion criteria
Wang 2011	Does not fulfil the intervention inclusion criteria
Wang 2013b	Does not fulfil the intervention inclusion criteria
Wang 2014	Does not fulfil the intervention inclusion criteria
Wang 2015	Review
Wang 2016	Does not fulfil the intervention inclusion criteria
Wei 1989	Does not fulfil the intervention inclusion criteria
Wen 2003	Does not fulfil the intervention inclusion criteria
Wu 2002	Does not fulfil the intervention inclusion criteria
Xia 1988	Does not fulfil the intervention inclusion criteria
Xia 2015	Does not fulfil the intervention inclusion criteria
Xu 1988	Does not fulfil the intervention inclusion criteria
Xu 1994	Does not fulfil the intervention inclusion criteria
Xu 1996	Not a randomised controlled trial
Xu 1999	Does not fulfil the intervention inclusion criteria
Xu 2011	Does not fulfil the intervention inclusion criteria
Xu 2016	Does not fulfil the intervention inclusion criteria
Xue 2012	Does not fulfil the intervention inclusion criteria
Yang 1992	Does not fulfil the intervention inclusion criteria
Yang 2002	Does not fulfil the intervention inclusion criteria
Yang 2007	Does not fulfil the intervention inclusion criteria
Ying 2010	Does not fulfil the intervention inclusion criteria
Yu 2015	Does not fulfil the intervention inclusion criteria
Zeng 1994	Does not fulfil the intervention inclusion criteria
Zhang 1998	Does not fulfil the intervention inclusion criteria
Zhang 1998b	Does not fulfil the intervention inclusion criteria
Zhang 1999	Does not fulfil the intervention inclusion criteria
Zhang 2000	Does not fulfil the intervention inclusion criteria
Zhang 2003	Does not fulfil the intervention inclusion criteria
Zhang 2005	Does not fulfil the intervention inclusion criteria
Zhang 2008	Does not fulfil the intervention inclusion criteria
Zhang 2008b	Does not fulfil the intervention inclusion criteria
Zhang 2012	Does not fulfil the intervention inclusion criteria
Zhang 2016	Does not fulfil the intervention inclusion criteria
Zhao 2014	Does not fulfil the intervention inclusion criteria
Zhao 2014b	Does not fulfil the intervention inclusion criteria
Zhou 1998	Does not fulfil the intervention inclusion criteria
Zhou 2002	Does not fulfil the intervention inclusion criteria
Zhou 2015	Does not fulfil the intervention inclusion criteria