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. 2016 Jul 13;36(28):7511–7522. doi: 10.1523/JNEUROSCI.0462-16.2016

Figure 5.

Figure 5.

Increased temperature enhances firing of DRG neurons expressing hNav1.7-A1632G mutant channels. Current-clamp recordings of DRG neurons at different temperatures. A, B, Percentages of spontaneously firing DRG neurons expressing Ala1632Gly (A, left panel) or WT (A, right panel) at 33°C, and Ala1632Gly (B, left panel) or WT (B, right panel) at 40°C. C, Responses of DRG neurons to depolarizing current steps at a set holding membrane potential (Vm) = −60 mV at 33°C (C, left panel), and 40°C (C, right panel). *p < 0.05 (repeated-measures two-way ANOVA with Bonferroni corrections; n = 8–10).