Table 1.
Nav1.7 | Spontaneously firing neurons | Resting membrane potential (mV) | Input resistance (mΩ) | Voltage threshold (mV) | Current threshold (pA) | Action potential amplitude (mV) | Action potential width at 0 mV (ms) |
---|---|---|---|---|---|---|---|
WT | 3 of 38, 7.9% | −52.0 ± 0.82 | 641 ± 71 | −28.6 ± 1.2 | 158 ± 20 | 122 ± 1.9 | 3.33 ± 0.30 |
A1632G | 12 of 48, 25%* | −50.2 ± 1.0 | 618 ± 55 | −31.6 ± 1.3 | 102 ± 16* | 126 ± 1.6 | 3.44 ± 0.27 |
p value | 0.0380 | 0.189 | 0.792 | 0.0953 | 0.0309 | 0.0941 | 0.782 |
*p < 0.05 A1632G versus WT channels.