Table 1.

Sexual behavior parameters during 5 consecutive days of mating^a

Group	Day 1	Day 2	Day 3	Day 4	Day 5
Intromission latency
Saline	716 ± 236 s	440 ± 161 s	842 ± 310 s	365 ± 162 s	42 ± 12 sb
CNO	434 ± 117 s	175 ± 64 s	315 ± 115 s	154 ± 49 s	42 ± 13 sb
Copulation efficiency [intromissions/( mounts + intromissions)]
Saline	0.8 ± 0.1	0.5 ± 0.1	0.6 ± 0.1	0.6 ± 0.0	0.7 ± 0.0
CNO	0.6 ± 0.0	0.7 ± 0.1	0.6 ± 0.1	0.6 ± 0.0	0.7 ± 0.1
Mounts (% of males)
Saline	70	80	90	90	91
CNO	91	91	73	100	91
Intromissions (% of males)
Saline	90	80	100	90	100
CNO	91	100	73	100	100
Ejaculations (% of males)
Saline	70	80	90	90	100
CNO	64	91	73	100	100

^aCNO did not affect sexual behavior during acquisition of sexual experience. Quantitative analysis of intromission latencies (in seconds), copulation efficiency, percentages of males that display mounts, intromissions, and ejaculations, during 5 consecutive days of sexual behavior in saline-pretreated (n = 10) and CNO-pretreated (n = 11) TH::Cre transgenic rats expressing G_i DREADD in VTA TH cells. Data represent mean ± SEM.

^bSignificant difference compared to day 1.