Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Oct 5;36(40):10296–10313. doi: 10.1523/JNEUROSCI.1823-16.2016

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016 the authors 0270-6474/16/3610297-18$15.00/0

PMC Copyright notice

Figure 10. — Dystroglycan is necessary for CCh-induced increase of inhibitory currents in pyramidal cells. A, Representative example traces of sIPSC recordings before (baseline, left trace) and after the application of CCh (right) in control mice. Average sIPSCs are shown above the traces. B, Cumulative frequency plots of IEIs and amplitudes of sIPSCs from traces in A. C, Comparison of average sIPSC frequency and amplitude before and after application of CCh in control slices. Application of CCh resulted in typical increase of IPSC frequency in control pyramidal cells, but amplitude was not affected by CCh. D, Representative example traces of sIPSC recordings before (baseline, left trace) and after the application of CCh (right trace) in DG cKO mice. Average sIPSCs are shown above the traces. E, Cumulative frequency plots of IEIs and amplitudes of sIPSCs from traces in D. F, Comparison of average sIPSC frequency and amplitude before and after application of CCh in DG cKO slices. In contrast to control slices, application of CCh did not lead to a significant increase of sIPSC frequency in DG cKO pyramidal cells. Data points represent individual cells. **p < 0.01.